{"id":20822,"date":"2017-04-04T19:56:51","date_gmt":"2017-04-04T19:56:51","guid":{"rendered":"http:\/\/www.oracletutoring.ca\/blog\/?p=20822"},"modified":"2017-04-04T19:56:51","modified_gmt":"2017-04-04T19:56:51","slug":"biology-what-is-non-competitive-inhibition","status":"publish","type":"post","link":"https:\/\/www.oracletutoring.ca\/blog\/biology-what-is-non-competitive-inhibition\/","title":{"rendered":"Biology:  what is non-competitive inhibition?"},"content":{"rendered":"<h1>Tutoring biology, non-competitive inhibition may be mentioned.  The tutor explains it.<\/h1>\n<p>In <a href=\"?p=20806\">yesterday&#8217;s post<\/a> I explain competitive inhibition.<\/p>\n<p>Non-competitive inhibition is similiar to competitive inhibition in that it hinders enzyme function.  The difference is that, with non-competitive inhibition, the inhibitor doesn&#8217;t bind to the enzyme&#8217;s active site; with competitive inhibition, it does.<\/p>\n<p>A non-competitive inhibitor may be a bulky atom such as a heavy metal, or a bulky molecule.  This bulky species will attach itself to the enzyme somewhere other than the active site.  However, the enzyme&#8217;s function is still impeded by one of two possible ways:<\/p>\n<ol>\n<li>The bulk of the inhibitor, though not occupying the active site, may still make it hard to reach, just as a long vehicle in a parking stall can prevent the use of the stall past it.<\/li>\n<li>The inhibitor may change the chemistry of the enzyme, making it less attractive to its intended substrate.<\/li>\n<\/ol>\n<p>HTH:)<\/p>\n<p>Source:<\/p>\n<p><u>Biology 12, module 1<\/u>.  Open School BC, 2007.<\/p>\n<p>Mader, S.  <u>Inquiry into Life<\/u>, 11th ed.  Toronto:  McGraw-Hill, 2006.<\/p>\n<p>Jack of <a href=\"https:\/\/www.oracletutoring.ca\">Oracle Tutoring by Jack and Diane,<\/a> Campbell River, BC.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Tutoring biology, non-competitive inhibition may be mentioned. The tutor explains it. In yesterday&#8217;s post I explain competitive inhibition. Non-competitive inhibition is similiar to competitive inhibition in that it hinders enzyme function. The difference is that, with non-competitive inhibition, the inhibitor &hellip;<\/p>\n<p class=\"read-more\"> <a class=\"more-link\" href=\"https:\/\/www.oracletutoring.ca\/blog\/biology-what-is-non-competitive-inhibition\/\"> <span class=\"screen-reader-text\">Biology:  what is non-competitive inhibition?<\/span> Read More &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[219,8],"tags":[28,2224],"class_list":["post-20822","post","type-post","status-publish","format-standard","hentry","category-biology","category-biology-12","tag-enzyme","tag-non-competitive-inhibition"],"_links":{"self":[{"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/posts\/20822","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/comments?post=20822"}],"version-history":[{"count":7,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/posts\/20822\/revisions"}],"predecessor-version":[{"id":20829,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/posts\/20822\/revisions\/20829"}],"wp:attachment":[{"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/media?parent=20822"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/categories?post=20822"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.oracletutoring.ca\/blog\/wp-json\/wp\/v2\/tags?post=20822"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}